Nucleophilic substitution

Chemical reaction in which a nucleophile is affixed to the substrate

In chemistry, a nucleophilic substitution (SN) is a class of chemical reactions in which an electron-rich chemical species (known as a nucleophile) replaces a functional group within another electron-deficient molecule (known as the electrophile). The molecule that contains the electrophile and the leaving functional group is called the substrate. The most general form of the reaction may be given as the following: Nuc : + R − LG ⟶ R − Nuc + LG : {\displaystyle {\text{Nuc}}\mathbf {:} +{\ce {R-LG -> R-Nuc}}+{\text{LG}}\mathbf {:} } The electron pair (:) from the nucleophile (Nuc) attacks the substrate (R−LG) and bonds with it.

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